Analgesics

NSAIDs COX inhibitors
- aspirin
- ibuprofen
- naproxen

Acetaminophen Treats mild-to-moderate pain; not an NSAID

Opioids Act at mu-opioid receptors
- morphine
- codeine
- tramadol

Ziconotide Given intrathecally to treat severe, chronic pain

Gabapentinoids
- Gabapentin
- pregabalin

Other drugs to treat neuropathic pain
- duloxetine
- amitriptyline
- carbamazepine

Topical Analgesics
- lidocaine
- ibuprofen or diclofenac-containing gels

Steroids may be injected into joints for long-term pain relief

Orphenadrine Used to treat muscle pain and help with motor control in patients with Parkinson's disease

Mexiletine An antiarrhythmic also used to treat chronic pain, often in cases of myotonic dystrophy

Combination Analgesics Often, analgesics are combined for synergistic effects
- acetaminophen/codeine
- acetaminophen/hydrocodone
- ibuprofen/oxycodone

Triptans Effective at treating pain/nausea from migraine
- sumatriptan
- zolmitriptan